Intellectual and Developmental Disabilities

To: Faculty of the Children’s Hospital of Philadelphia and the Perelman School of

Medicine at the University of Pennsylvania

(Please distribute to eligible faculty)

From: Michael B. Robinson, Ph.D. & Robert Schultz, Ph.D. (Directors, IDDRC)

Date: January 14, 2019

Re: New Program Development Award for the Institutional Intellectual and

Developmental Disabilities Research Center at CHOP/Penn (applications due

March 11, 2019)

We are pleased to announce the availability of funding to support pilot projects relevant to

elucidating the causes of and/or developing potential new therapies for intellectual or

developmental disabilities. These pilot projects may be basic, translational, or clinical

research. The goals of this program are to help junior faculty integrate into the IDDRC and

to develop strong externally funded research programs in this area.

This program was previously supported as part of the Institutional Intellectual and

Developmental Disabilities Research Center at CHOP/Penn with funding from the Eunice

Kennedy Shriver National Institutes of Child Health and Human Development (NICHD)

when the Center was supported as a P30 mechanism (see attached list of prior awardees).

With the most recent competitive renewal, the mechanism switched to a U54 and the New

Program Development was excluded from eligibility. Thankfully, Drs. Bryan Wolf and

Jonathan Epstein agreed to provide funding so that the program could be reinstated.

This year, we anticipate making 1 award of up to $50,000 per year for two years. The

second year of support is contingent upon demonstration of adequate progress.

Applications will be reviewed by a subgroup of the IDDRC Steering Committee.

Eligibility Requirements:

1. Individuals must hold a faculty appointment as an Assistant Professor for less than

four years from the date of appointment by July 1, 2019 even if the initial

appointment was at another institution. Academic Clinicians are not eligible for this

award.

2. None of the funding can be used to support the salary of the Principal Investigator

(support for salaries of technical staff and trainees is acceptable). K awardees are

encouraged to develop projects that are non-overlapping extensions of their funded

K awards (the goal will be to subsume the effort required for the pilot project under

the K award). All others will need to commit a reasonable percentage of effort to the

pilot project (generally 5-10%). This will be cost-sharing supported by either the

Children’s Hospital of Philadelphia or the University of Pennsylvania (presumably

from start-up funds).

Application Information (in the following order):

1. Please provide a title page that includes the title of the project, name and academic

title of the Principal Investigator, date of faculty appointment (If initial appointment

occurred at another institution, this is the date you would use.), and contact

information.

2. Provide an abstract for the project (no more than 250 words) that clearly describes

the overall project.

3. NIH Biosketch (current format), including past, present, and pending grant support.

4. Research Activities. Please provide a list of projects underway—even if they are

supported by internal sources—with brief summaries (1-2 sentences each) for each

project.

5. Research Plan, including specific aims, significance/innovation, and experimental

approach. We recommend one page for specific aims, 1/2 page for significance, 1/2

page for innovation, and three pages for experimental approach (note the total

length cannot exceed five pages - excluding literature cited).

Please Note: The Center supports core activities, including Clinical Translational

Core, Biostatistics and Bioinformatics Core, Analytical Neurochemistry Core,

Neuroimaging and Neurocircuitry Core, and Preclinical Models Core. For

descriptions of services and contact information, please contact Kristen Pidgeon

(pidgeonk [at] email.chop.edu) or visit our website:

http://iddrc.research.chop.edu/. Applicants are encouraged to describe how usage

of these cores will facilitate the goals of the pilot project. Also, please articulate a

plan for securing external continued support for the program.

6. A letter of nomination from the Department Chair or Division Chief that describes

the applicant’s qualifications for the award and the institutional commitment to the

candidate. This letter should include an explicit statement that effort for the project

will be supported by institutional funds, if needed. This letter can be sent separately

to Kristen Pidgeon (pidgeonk [at] email.chop.edu) or included in the application

packet.

7. A budget and brief budget justification. Please keep in mind the eligibility

criteria—salary support cannot be included. 5-10% of effort will be expected.

If there are questions regarding the application process, please contact Kristen Pidgeon

(pidgeonk [at] email.chop.edu or 215-590-3728).

Applications (assembled as a single PDF) are due Monday, March 11, 2019 to: Kristen

Pidgeon, Research Program Manager - pidgeonk [at] email.chop.edu

Applicants selected for support will be notified as soon as possible. Anticipated start date

for funding is July 1, 2019.