Abramson Cancer Center and Cardiovascular Institute, Penn Cardio-Oncology Center of Excellence

 

Abramson Cancer Center and Cardiovascular Institute

Penn Cardio-Oncology Center of Excellence

Request for Applications (RFA) for Collaborative Pilot Projects

Release Date: December 21, 2018

Due Date: February 20, 2019

Notification Date: April 1, 2019

The Penn Cardio-Oncology Center of Excellence is soliciting proposals for pilot studies that focus on developing new collaborations between investigators across cancer and cardiovascular medicine. This funding mechanism will focus on addressing fundamental problems in cardio-oncology. Innovative cancer research projects that have the potential for future peer review funding will receive priority. Proposals can be basic, translational or clinical in focus.

This Penn Cardio-Oncology Center of Excellence Pilot Program will commit to supporting pilot grants for up to $50,000 in total costs. Funding will be allocated over one year and is expected to provide the support needed to conduct pilot studies that will serve as preliminary data for an R01-type grant application, and would be suitable for publication in a peer-reviewed, academic journal.

Projects must be jointly led by at least one PI who is a member of the ACC/Hematology and Oncology Division and one PI who is a member of CVI/Cardiovascular DIvision. Priority will be given to new collaborations (i.e., the PIs are not already involved in an existing multi-PI grant). Investigators at all faculty levels are invited to apply.

Awards cannot be used to support research that is already funded by an external agency. If funded, a progress report is required within 6 months of the end of the funding period and awardees must present their findings to the Cardio-Oncology Center of Excellence Steering Committee within 6 months of the end of the funding cycle.

REVIEW PROCESS

Proposals will undergo peer review by the Penn Cardio-Oncology Center of Excellence Steering Committee. Applications will be evaluated for scientific impact and innovation, experimental rigor, the ability to seed new collaborations, and the potential to generate external funding. Applications must include specific plans and time-lines for submission of a multi-PI NIH grant based on the data collected from the proposed pilot study. Successful applicants will be notified by April 1, 2019. Funding will have a start date of June 1, 2019, contingent on all required regulatory approvals being in place (e.g. IACUC and IRB approvals).

PROPOSAL SUBMISSION INSTRUCTIONS

Proposal due date: February 20, 2019

Please email proposals to Joanna Acosta (joanna.acosta [at] uphs.upenn.edu) and Bonnie Ky, MD, MSCE (bonnie.ky [at] uphs.upenn.edu) as a single PDF file with the subject title "Penn Cardio-Oncology Center of Excellence Pilot Grant".

A complete proposal must include:

a) Title of application

b) Joint PI information: names, positions, titles, and contact information

c) Abstract (1/2 page max)

d) Specific Aims (1/2 page max)

e) Preliminary Data (if any), Significance, Innovation, and Approach (2 pages max)

f) References (1 page max)

g) No appendices are allowed

h) Budget

i) NIH Biosketches of PIs

Items (c)-(e) must not exceed 3 pages.

Please use Arial 11 single-spaced font, with ½ inch margins all around.

Please designate a primary corresponding PI.

Project duration: 1 year

Project start date: June 1, 2019

For scientific questions, please contact members of the Penn Cardio-Oncology Center of Excellence Steering Committee: Bonnie Ky, MD, MSCE (bonnie.ky [at] uphs.upenn.edu); Joseph Carver (joseph.carver2 [at] uphs.upenn.edu); Sandra Ryeom (sryeom [at] upenn.edu); Richard Aplenc (raplenc [at] email.chop.edu)

For administrative-related questions, please contact: Joanna Acosta at joanna.acosta [at] uphs.upenn.edu or 215 573 6606 or Bonnie Ky, MD, MSCE at bonnie.ky [at] uphs.upenn.edu